Operation Method of Lab Benchtop Manifold Freeze Dryer
Operation Method of Lab Benchtop Manifold Freeze Dryer
Lab benchtop manifold freeze dryer in daily life is very common, but many people are not very clear about how to use the freeze dryer specific, for the lab benchtop manifold freeze dryer matters need attention is not very understand, let’s go to a more comprehensive understanding of the lab benchtop manifold freeze dryer. First of all, let’s take a look at the operation of the freeze dryer.
Preparation of the lab benchtop manifold freeze dryer before the operation 1. When the freeze-drying machine is used for the first time, all parts of the instrument must be thoroughly cleaned. The parts of the stainless steel shall be cleaned with ethanol, and the plexiglass shall be cleaned with normal saline. Ampoules are cleaned by ultrasonic cleaning machine. 2. Before the freeze-drying has to be frozen, still need to prepare low-temperature refrigerator, minus 40 degrees Celsius, or low-temperature refrigerator is minus 80 degrees Celsius, the prepared to dry goods in the low-temperature refrigerator or liquid nitrogen, need four hours or so commonly, can be observed directly from outside, items after completely frozen solid, can only be the freeze-drying experiments, move items quickly freeze drier within a tray, in order to guarantee the freeze-drying effect. 3. The main engine and lab single stage rotary vane vacuum pump are connected by a green vacuum tube, and the connection uses an international standard clamp. In order to effectively prevent air leakage, the hoop is designed with a sealed rubber ring.
On the method to prevent air leakage, apply the proper amount of vacuum grease on the rubber ring, and then use the clamp to tighten, which can make the connection more closely fit together. If there is no clamp, it will cause air leakage, and the digital display value on the instrument panel is greater than 20PA during vacuum extraction. At this time, the airtightness of the lab single stage rotary vane vacuum pump and the lab benchtop manifold freeze dryer glass cover should be checked. 4. There are two power sockets on the right board of the freeze-dryer. One connects the power line of the vacuum pump to the host and then plugs the main power supply of the second freeze-dryer into the power supply. 5. Before the operation of the vacuum pump must check whether to add the vacuum pump oil, otherwise, it can not operate normally. The oil surface should not be lower than the middle line of the oil mirror, the lab single stage rotary vane vacuum pump at the beginning of the use of a relatively strong jitter slowly will become stable. 6. If the airtightness is not good, some vacuum grease should be applied to the sealed rubber ring above the cold trap, and the plexiglass cover should be gently turned on the rubber ring to test the airtightness before opening the vacuum pump. To ensure the integrity of the chi closure. The operation method of lab benchtop manifold freeze dryer.
1. The boot 2. Pre-freezing: put the sample tray into the pre-freezing rack and place it in the cold trap. The thermometer probe is placed on the upper sample tray and the sealing cover is covered. Click the “refrigerator” switch on the screen and prefreeze for 3 hours. 3. Replace the drying rack — After the pre-freezing, take the sample tray out of the cold trap and quickly put it into the drying rack. Put the drying rack above the cold trap, cover with organic glass, and the dryer fully contact with the bottom “O” type sealing ring. 4. Drying — Check whether the inflation valve is tightened, click the “vacuum gauge” on the screen, for example, the vacuum degree is 110kPa, click the “vacuum pump”, lab single stage rotary vane vacuum pump is opened and operated, the vacuum degree rapidly drops to below 20Pa, which is normal. 5. Dryness inspection — after a certain period of the drying operation, check the sample curve and the apparent feeling sample has been completely dried, and slowly unscrew the gas valve to make the pressure in the lab benchtop manifold freeze dryer rise to 110kPa.Click “Vacuum Pump” to close the vacuum pump. Click “vacuum gauge” to close the vacuum gauge. 6. End drying — remove the plexiglass cover and take out the sample tray from the drying rack. Click “Refrigerant” to close the compressor. 7. Ending — After the water in the cold trap melts, it flows out from the gas valve, pays attention to receive. 8. After each use, be sure to record the use time, accumulative 300 hours, and change the oil
Startup and stop operation process of lab benchtop manifold freeze dryer 1. Open the main power switch on the left side of the chassis, and the air pressure digital display is 110PK of atmospheric pressure; 2. Press and hold the total open key on the control panel for more than three seconds, and the temperature is the actual temperature of the cold trap; 3. Start the refrigerator and pre-cool it for more than 30 minutes; 4. Put the sample into the sample rack, cover the plexiglass cover, and start the lab single stage rotary vane vacuum pump; 5. Record the temperature and pressure values after the air pressure digital display stabilizes.
Downtime 1. Record the temperature and pressure before the shutdown; 2. Press and hold the air charging valve of the control panel, and immediately close the vacuum pump; 3. Open the plexiglass cover and take out the sample when the air pressure is atmospheric; 4. Turn off the refrigerator, press the on-off key for more than three seconds, and finally turn off the main power switch; 5. After the ice in the cold well has completely melted into water, open the outlet valve on the left side of the cabinet to release water, clean the inner wall of the cold well with a dry cloth, and cover the cold well with a large piece of filter paper to prevent dust.
Precautions for lab benchtop manifold freeze dryer: 1. The surface area of the sample shall be enlarged as far as possible, and no acid and alkali substances and volatile organic solvents shall be included in the sample. 2. The sample must be completely frozen into ice. If there is any residual liquid, it will cause gasification jet; 3. Note that the cold trap is about 65 degrees below zero, which can be used as a cryogenic refrigerator, but it must be operated with insulating gloves to prevent frostbite; 4. Before starting the lab single stage rotary vane vacuum pump, check whether the water outlet valve is tightened, whether the air charging valve is closed, and whether the contact surface between the plexiglass cover and the rubber ring is clean and sealed; 5. In general, the machine shall not be used continuously for more than 48 hours; 6. During the freezing process, the temperature of the sample decreases gradually. After the sample is taken out and warmed for a period of time (it is still in the frozen state), the sample can be continued to dry to shorten the drying time.